47045-GAB-Z-MOH-1 The Global Fund to Fight AIDS, Tuberculosis and Malaria Gabon, Multicomponent, Ministry of Health of the Gabonese Republic Goals: Réduire les nouvelles infections du VIH de 95% d'ici 2027 / Reduce new HIV infections by 95% by 2027; Réduire le taux de transmission du VIH de la mère à l'enfant de 13% à 7% d'ici 2027 / Reduce the rate of mother-to-child transmission of HIV from 13% to 7% by 2027; Réduire le nombre des décès liés au VIH de 95% d'ici 2027 / Reduce HIV-related deaths by 95% by 2027; Assurer la protection sociale, le soutien, le respect des droits humains, du genre et de l'équité dans la réponse nationale au VIH / Ensure social protection, support, respect for human rights, gender and equity in the national response to HIV; D’ici 2027, contribuer à une réduction 7% de l’incidence liée à la tuberculose au Gabon c'est-à-dire passer d’une incidence de 509 cas en 2022 à 480 cas pour 100 000 habitants / By 2027, contribute to a 7% reduction in the incidence of tuberculosis in Gabon, i.e. go from an incidence of 509 cases in 2022 to 480 cases per 100,000 inhabitants; D’ici 2027, contribuer à la réduction de la mortalité de 80 décès pour 100 000 habitants en 2022 à 71 décès/100,000 habitants dues à la tuberculose. / By 2027, contribute to the reduction of mortality from 80 deaths per 100,000 inhabitants in 2022 to 71 deaths/100,000 inhabitants due to tuberculosis; D’ici 2027, réduire d’au moins 65%, l’incidence et la mortalité liées au paludisme par rapport à 2021 / By 2027, reduce at least 65% of malaria incidence and mortality compared to 2021. Objectives: Reduire les nouvelles infections au VIH de 1900 en 2022 à 816 en 2027 / Reduce new HIV infections from 1900 in 2022 to 816 in 2027; Reduire la mortalité liée au VIH de 1800 décès en 2022 à 800 en 2027 /Reduce HIV-related mortality from 1,800 deaths in 2022 to 800 in 2027; Augmenter la notification des cas de tuberculose nouveaux cas et rechutes de tuberculose de 6575 en 2023 à 10157 en 2027 et avoir un succés thérapeutique pour 86% des cas mis sous traitement / Increase the notification of new cases and relapses of tuberculosis from 6,575 in 2023 to 9,399 in 2027 and have therapeutic success for 86% of cases put under treatment; Augmenter de 90 cas de TB-RR et ou TB-MR en 2022 à 222 cas en 2027 la notification des patients annuellement mis sous traitement pour une tuberculose multi-résistante ou résistante à la rifampicine et atteindre un taux de succès thérapeutique d'au moins 63% en 2027. / Increase from 90 cases of RR-TB and/or MDR-TB in 2022 to 222 cases in 2027 the notification of patients annually placed on treatment for multi-drug-resistant or rifampicin-resistant tuberculosis and achieve a therapeutic success rate of at least 63% in 2027; Effectuer en 2027 le depistage VIH chez 92% des nouveaux cas et rechutes et mettre sous therapie préventive au moins 10% des personnes vivant avec le VIH éligible. / Carry out HIV screening in 92% of new cases and relapses in 2027 and put at least 10% of eligible people living with HIV on preventive therapy; Augmenter le pourcentage des patients atteints de TB enregistrés nouveaux cas et rechutes dont le statut sérologique VIH est documenté, de 53% en 2023 à 92% en 2027 / Increase the percentage of TB patients registered new cases and relapses whose HIV serological status is documented, from 53% in 2023 to 92% in 2027. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic Ministry of Health of the Gabonese Republic The Global Fund to Fight AIDS, Tuberculosis and Malaria The Global Fund to Fight AIDS, Tuberculosis and Malaria Communications +41 58 791 1700 website@theglobalfund.org https://www.theglobalfund.org The Global Fund to Fight AIDS, Tuberculosis and Malaria, Global Health Campus, Chemin du Pommier 40, 1218 Grand-Saconnex, Geneva, Switzerland The Global Fund to Fight AIDS, Tuberculosis and Malaria Grant Management Division Plaikessi Kouadjani Fund Portfolio Manager +41 58 791 1700 plaikessi.kouadjani@theglobalfund.org https://www.theglobalfund.org The Global Fund to Fight AIDS, Tuberculosis and Malaria, Global Health Campus, Chemin du Pommier 40, 1218 Grand-Saconnex, Geneva, Switzerland Gabon Tuberculosis Malaria HIV Multicomponent, RSSH Ensure healthy lives and promote well-being for all at all ages End the epidemics of AIDS, tuberculosis, malaria and neglected tropical diseases, and combat hepatitis, water-borne diseases and other communicable diseases Achieve universal health coverage HIV -> Differentiated HIV Testing Services -> Facility-based testing outside of key population (KP) and adolescent girls and young women (AGYW) programs HIV -> Elimination of vertical transmission of HIV, syphilis and hepatitis B -> Early infant diagnosis and follow-up HIV testing for exposed infants HIV -> Elimination of vertical transmission of HIV, syphilis and hepatitis B -> Integrated testing of pregnant women for HIV, syphilis and hepatitis B HIV -> Prevention package for men who have sex with men (MSM) and their sexual partners -> HIV prevention communication, information and demand creation for MSM HIV -> Treatment, care and support -> Diagnosis and management of advanced HIV disease (adults and children) HIV -> Treatment, care and support -> Treatment monitoring - Viral load and antiretroviral (ARV) toxicity Malaria -> Vector control -> Insecticide treated nets (ITNs) - Mass campaign: universal Multicomponent -> Program management -> Coordination and management of national disease control programs Multicomponent -> Program management -> Grant management RSSH -> RSSH: Monitoring and evaluation systems -> Analyses, evaluations, reviews and data use RSSH -> RSSH: Monitoring and evaluation systems -> Data quality RSSH -> RSSH: Monitoring and evaluation systems -> Surveillance for HIV, tuberculosis and malaria Tuberculosis -> Drug-resistant (DR)-TB diagnosis, treatment and care -> DR-TB diagnosis/drug susceptibility testing (DST) Tuberculosis -> Drug-resistant (DR)-TB diagnosis, treatment and care -> DR-TB treatment, care and support Tuberculosis -> Key and vulnerable populations (KVP) - TB/DR-TB -> KVP - Children and adolescents Tuberculosis -> Key and vulnerable populations (KVP) - TB/DR-TB -> KVP - Miners and mining communities Tuberculosis -> Key and vulnerable populations (KVP) - TB/DR-TB -> KVP - People in prisons/jails/detention centers Tuberculosis -> Removing human rights and gender related barriers to TB services -> Community mobilization and advocacy, including support to TB survivor-led groups Tuberculosis -> Removing human rights and gender related barriers to TB services -> Eliminating TB-related stigma and discrimination Tuberculosis -> TB diagnosis, treatment and care -> TB screening and diagnosis Tuberculosis -> TB diagnosis, treatment and care -> TB treatment, care and support Tuberculosis -> TB/DR-TB Prevention -> Infection prevention and control (IPC) Tuberculosis -> TB/DR-TB Prevention -> Preventive treatment Tuberculosis -> TB/HIV -> TB/HIV - Collaborative interventions Tuberculosis -> TB/HIV -> TB/HIV - Community care delivery Tuberculosis -> TB/HIV -> TB/HIV - Screening, testing and diagnosis Tuberculosis -> TB/HIV -> TB/HIV - Treatment and care 1793355.98 3699725.14 1303057.99 4656977.73 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 728591.63 Global Fund disbursement to GAB-Z-MOHP01 (Government). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 158879.12 Global Fund disbursement to GAB-Z-MOHP01 (Other 3rd Party). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 85807.89 Global Fund disbursement to GAB-Z-MOHP01 (Other 3rd Party). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 9291.54 Global Fund disbursement to GAB-Z-MOHP01 (Other 3rd Party). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 158517.03 Global Fund disbursement to GAB-Z-MOHP01 (Other 3rd Party). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 159770.07 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 325525.49 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -159770.07 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 69810.23 Global Fund disbursement to GAB-Z-MOHP01 (Other 3rd Party). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -325525.49 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 641124.28 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -641124.28 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 641127.09 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 187.12 Funds returned to the Global Fund from GAB-Z-MOHP01 (Other 3rd Party). Ministry of Health of the Gabonese Republic The Global Fund to Fight AIDS, Tuberculosis and Malaria -187.12 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 639433.80 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -641127.09 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 145463.03 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -369124.81 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 369105.64 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 124845.96 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 53694.46 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 35645.28 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 867.86 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 3585.12 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 265541.96 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -275312.94 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 261739.26 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -265541.96 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 13157.97 Funds returned to the Global Fund from GAB-Z-MOHP01 (Other 3rd Party). Ministry of Health of the Gabonese Republic The Global Fund to Fight AIDS, Tuberculosis and Malaria 6288.53 Funds returned to the Global Fund from GAB-Z-MOHP01 (Other 3rd Party). Ministry of Health of the Gabonese Republic The Global Fund to Fight AIDS, Tuberculosis and Malaria -13157.97 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -6288.53 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 286258.41 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -24519.15 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -261739.26 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 24519.15 Funds returned to the Global Fund from GAB-Z-MOHP01 (Pooled Procurement Mechanism). Ministry of Health of the Gabonese Republic The Global Fund to Fight AIDS, Tuberculosis and Malaria -286258.41 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 55742.11 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 8703.43 Global Fund disbursement to GAB-Z-MOHP01 (Other 3rd Party). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 44900.35 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 217155.62 Global Fund disbursement to GAB-Z-MOHP01 (Other 3rd Party). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 134054.92 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -10841.76 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 141992.03 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -134054.92 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 133475.30 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -141992.03 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 134616.63 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -133475.30 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 263875.79 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -134616.63 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 108721.58 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -155154.21 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 171310.66 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 170704.99 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -171310.66 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 3424172.78 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -3220221.24 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 2524641.26 Global Fund disbursement to GAB-Z-MOHP01 (Government). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 13530.50 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 101225.55 Global Fund disbursement to GAB-Z-MOHP01 (Other 3rd Party). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 5648.67 Global Fund disbursement to GAB-Z-MOHP01 (Other 3rd Party). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 3275.54 Funds returned to the Global Fund from GAB-Z-MOHP01 (Pooled Procurement Mechanism). Ministry of Health of the Gabonese Republic The Global Fund to Fight AIDS, Tuberculosis and Malaria 8088.02 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 35839.91 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 9321.44 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -3275.54 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 4380.37 Global Fund disbursement to GAB-Z-MOHP01 (Pooled Procurement Mechanism). The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 95237.40 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic -99544.75 Global Fund commitment to GAB-Z-MOHP01. The Global Fund to Fight AIDS, Tuberculosis and Malaria Ministry of Health of the Gabonese Republic 1429353.73 Expenditure reported by Ministry of Health of the Gabonese Republic for GAB-Z-MOHP01, Jan 2025 to Dec 2025. Ministry of Health of the Gabonese Republic An overview of a grant over its lifetime. General terms and conditions which apply to Global Fund grants. Funding Request of funding request FR1623-GAB-Z. Funding Request of funding request FR1623-GAB-Z. 1 - (1) In accordance with the Global Fund’s Sustainability, Transition and Co-financing Policy (GF/B35/04) (the “STC Policy”), the commitment and disbursement of EUR 1,602,855 (the “Co-Financing Incentive”), is subject to the Global Fund’s satisfaction of the Grantee’s compliance with the requirements listed at 6.1(1)(a) and 6.1(1)(b) below (“Co-Financing Requirements”). The Principal Recipient acknowledges and agrees that the Global Fund may reduce Grant Funds during the current or any subsequent Implementation Period in the event the Grantee fails to: (a) progressively increase government expenditure on health to meet national universal health coverage goals; and/or (b) increase domestic funding of Global Fund-supported programs, with a focus on progressively absorbing the key costs of national disease plans, as identified in consultation with the Global Fund. (2) In order to satisfy the Co-Financing Requirements, the Grantee shall, as set out in “Engagement des gouvernements relatif au cofinancement des ripostes nationales soutenues par Ie Fonds Mondial”, dated 12 September 2024 (the “Commitment Letter”), unless otherwise agreed in writing by the Global Fund: (a) fulfil a total minimum co-financing commitment of EUR 17,569,424 from 2025-2027 (inclusive), comprising investments in: i. HIV of EUR 4,686,261; ii. TB of EUR 5,126,190; and iii. Malaria of EUR 7,756,973; (b) fulfil the programmatic commitments as stipulated in Table 3 of the Commitment Letter; and (c) provide to the Global Fund, by no later than 31 March of each year of the Implementation Period and the year following the end of the Implementation Period, evidence supporting achievement of the Co-Financing Requirements, including: i. the approved annual budget for HIV / TB / Malaria for the upcoming year; and ii. the total expenditure for HIV / TB / Malaria in the previous fiscal year. (d) The Grantee shall, as set out in Section 4 of the Commitment Letter, provide evidence to the Global Fund of an approved budget allocation for financing 100% of the procurement of universal insecticide-treated mosquito nets (ITN) and associated shipping and handling costs amounting to EUR 7,125 964 to conduct the ITN mass distribution campaign (the "ITN Mass Campaign"). i. Subject to the Global Fund’s satisfaction of the Grantee’s compliance with the requirements listed at 6.1 (2) (d), and without prejudice to the terms and conditions of this Grant Agreement, the Principal Recipient acknowledges that the Global Fund will match up to 50% of the total cost of the ITN Mass Campaign, (i.e. up to EUR 3,220,800), in accordance with international best practices, as outlined by the World Health Organization (WHO) and the Alliance for Malaria Prevention (AMP). 2 - The procurement of Health Products shall be carried out through the Pooled Procurement Mechanism (“PPM”) of the Global Fund, unless the Global Fund directs the Principal Recipient otherwise in writing. The Principal Recipient has all the necessary power and authority to execute, deliver and carry out its obligations under the wambo.org – PPM registration letter in the form approved by the Global Fund. 3 - (1) Grant Funds may be used to pay for the services of an external auditor or for a Supreme Audit Institution approved by the Global Fund retained by the Global Fund for the annual independent audit of the Program (the “External Auditor”) and the Global Fund may disburse such Grant Funds directly to the External Auditor; (2) the Principal Recipient consents to the carrying out of audits of the Program by the External Auditor for the period covering fiscal years 2025, 2026 and 2027 (and other such additional periods as the Global Fund may communicate to the Principal Recipient in writing, and to the terms of reference of the External Auditor and agrees that such terms of reference may be amended from time to time; and (3) without limiting Section 7.5 of the Global Fund Grant Regulations (as amended from time to time), the Principal Recipient shall cooperate fully with the External Auditor to allow the External Auditor to perform its services, including by providing all information and documents requested by the External Auditor or the Global Fund. 4 - No later than 30 April 2025, the Principal Recipient shall submit to the Global Fund and obtain the Global Fund’s prior written approval of a procedures manual that shall describe in detail the following, without limitation: (1) the roles and responsibilities of Program staff; (2) recruitment procedures for Program staff; (3) disbursement procedures to Sub-recipients and Suppliers; and (4) procurement procedures for Program goods and services. 5 - No later than 30 September 2025, the Principal Recipient shall submit to the Global Fund and obtain the Global Fund’s prior written approval of, an updated national monitoring and evaluation plan. 6 - Prior to the use of budget lines 37, 44 and 49 of the Grant budget by the Principal Recipient to treat DR-TB patients activities, to procure a generator for the Nkembo Hospital and for the mapping and the biological and behavioral survey for key populations, the Principal Recipient shall submit to the Global Fund, and obtain the Global Fund’s written approval of, a detailed budget and implementation plan for these activities. Module: Drug-resistant (DR)-TB diagnosis, treatment and care. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative. Module: Drug-resistant (DR)-TB diagnosis, treatment and care. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative. Numerator: 107; Denominator: 118; Percentage: 90.68%. Numerator: 105; Denominator: 107; Percentage: 98.13%. Numerator: 2; Denominator: 107; Percentage: 1.87%. Numerator: 43; Denominator: 107; Percentage: 40.19%. Numerator: 64; Denominator: 107; Percentage: 59.81%. Numerator: 84; Denominator: 107; Percentage: 78.5%. Numerator: 186; Denominator: 186; Percentage: 100%. Numerator: 92; Denominator: 99; Percentage: 92.93%. Numerator: 89; Denominator: 92; Percentage: 96.74%. Numerator: 3; Denominator: 92; Percentage: 3.26%. Numerator: 39; Denominator: 92; Percentage: 42.39%. Numerator: 53; Denominator: 92; Percentage: 57.61%. Numerator: 79. Numerator: 204; Denominator: 204; Percentage: 100%. Numerator: 222; Denominator: 222; Percentage: 100%. Module: Drug-resistant (DR)-TB diagnosis, treatment and care. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative. Numerator: 36; Denominator: 69. Numerator: 89; Denominator: 150. Numerator: 31; Denominator: 51. Numerator: 102; Denominator: 168. Numerator: 117; Denominator: 186. Module: Elimination of vertical transmission of HIV, syphilis and hepatitis B. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative - special. Numerator: 742; Denominator: 2140. Numerator: 1031; Denominator: 2066. Numerator: 380; Denominator: 2300. Numerator: 1120; Denominator: 2014. Numerator: 1258; Denominator: 1964. Module: Elimination of vertical transmission of HIV, syphilis and hepatitis B. Geographic coverage: Subnational, 100% of national program target. Aggregation: Non cumulative - special. Numerator: 23828; Denominator: 36659. Numerator: 30953; Denominator: 41271. Numerator: 26841; Denominator: 34822. Numerator: 37105; Denominator: 46381. Numerator: 47386; Denominator: 55748. Module: TB diagnosis, treatment and care. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative. Module: TB diagnosis, treatment and care. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative. Numerator: 2411; Denominator: 6299. Numerator: 3631; Denominator: 8069. Numerator: 4144; Denominator: 6598. Numerator: 5242; Denominator: 8737. Numerator: 7049; Denominator: 9399. Module: TB diagnosis, treatment and care. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative. Numerator: 336; Denominator: 6575. Numerator: 850; Denominator: 8737. Numerator: 1016; Denominator: 9399. Module: TB diagnosis, treatment and care. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative. Numerator: 2348; Denominator: 3593. Numerator: 5940; Denominator: 8027. Numerator: 2138; Denominator: 2949. Numerator: 6455; Denominator: 8069. Numerator: 7514; Denominator: 8737. Module: TB/HIV. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative. Numerator: 922; Denominator: 985. Numerator: 907; Denominator: 961. Numerator: 10; Denominator: 17. Numerator: 5; Denominator: 7. Numerator: 498; Denominator: 540. Numerator: 424; Denominator: 445. Numerator: 1619; Denominator: 1704. Numerator: 772; Denominator: 991. Numerator: 760; Denominator: 975. Numerator: 10; Denominator: 11. Numerator: 2; Denominator: 5. Numerator: 405; Denominator: 506. Numerator: 367; Denominator: 485. Numerator: 2040; Denominator: 2126. Numerator: 2512; Denominator: 2590. Module: TB/HIV. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative - special. Numerator: 1769; Denominator: 28659. Numerator: 3086; Denominator: 36737. Numerator: 3844; Denominator: 39222. Module: TB/HIV. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative. Numerator: 3486; Denominator: 6575. Numerator: 5679; Denominator: 8069. Numerator: 2692; Denominator: 6598. Numerator: 7085; Denominator: 8737. Numerator: 8633; Denominator: 9399. Module: Treatment, care and support. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative - other. Numerator: 543; Denominator: 2262. Numerator: 767; Denominator: 1827. Numerator: 767; Denominator: 2400. Numerator: 815; Denominator: 1663. Numerator: 836; Denominator: 1520. Module: Treatment, care and support. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative - other. Numerator: 9838; Denominator: 28659. Numerator: 265; Denominator: 1007. Numerator: 669; Denominator: 742. Numerator: 73; Denominator: 742. Numerator: 22239; Denominator: 34125. Numerator: 9156; Denominator: 35334. Numerator: 8874; Denominator: 34730. Numerator: 282; Denominator: 604. Numerator: 2934; Denominator: 10358. Numerator: 27553; Denominator: 36737. Numerator: 33338; Denominator: 39222. Module: Treatment, care and support. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative - other. Numerator: 28569; Denominator: 48614. Numerator: 19141; Denominator: 28569. Numerator: 8885; Denominator: 28569. Numerator: 34125; Denominator: 49527. Numerator: 35334; Denominator: 52000. Numerator: 24672; Denominator: 35344. Numerator: 10662; Denominator: 35344. Numerator: 36737; Denominator: 49587. Numerator: 39222; Denominator: 49645. Module: Treatment, care and support. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative - special. Numerator: 1757; Denominator: 2140. Numerator: 1777; Denominator: 2066. Numerator: 1846; Denominator: 2300. Numerator: 1792; Denominator: 2014. Numerator: 1787; Denominator: 1964. Module: Vector control. Geographic coverage: National, 100% of national program target. Aggregation: Non cumulative.